心血管疾病中内皮细胞调控机制的研究进展
DOI:
https://doi.org/10.70693/cjmsr.v1i1.554Keywords:
心血管疾病；内皮细胞；功能失调；分子机制；治疗靶点Abstract
疾病是全球范围内死亡和致残的关键之一，其中血管内皮细胞功能障碍在疾病发生与进展中发挥了至关重要的作用。血管内皮细胞通过一氧化氮（NO）和内皮素（ET）等活性分子血管死亡，参与死亡反应与血管新生等过程。近年来，随着分子生物学与组学技术的飞速发展，内皮细胞机制在氧化、本综述系统概述了内皮细胞的结构功能、功能缓解的分子机制及其在动脉粥样硬化、高血压、心力衰竭等心血管疾病中的关键作用，探讨了相关的治疗靶点和干预策略，最后对当前研究挑战及未来展望进行了总结。深入了解内皮细胞调节机制对心血管疾病的新型治疗策略提供了重要思路。
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