坏死性凋亡在糖尿病性创面愈合中的研究进展
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https://doi.org/10.70693/cjmsr.v1i1.688关键词:
糖尿病性创面;坏死性凋亡;相关蛋白;研究进展摘要
糖尿病是一种目前临床上常见的慢性代谢性疾病,并发症多,尤其是糖尿病足可导致患者残疾,甚至死亡,具有易诊断、治疗难、治疗周期长、医疗费用高且容易复发等特点,严重影响患者的生活质量及身心健康,给个人、家庭和社会造成了沉重的负担。因此,如何提高糖尿病性创面的治愈率已成为急需解决的难题。坏死性凋亡是近年来发现的一种新型的细胞程序性死亡途径,可参与多种炎症反应。研究表明,细胞坏死性凋亡参与糖尿病的发病过程,在糖尿病性创面愈合中扮演着极其重要的作用。本文通过阐述细胞坏死性凋亡与创面相关蛋白的研究及其在糖尿病性创面中的作用机制,为临床治疗糖尿病性创面提供借鉴。
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